嗅觉出了问题？你可能是新冠病*携带者
经过近3个月艰苦磨练，全球的临床医生和科学家逐渐掌握了新型冠病*Covid-19感染及其致病规律。我们借助图解分享一下(原图来源)。
由于SARS-CoV2病*进入人体呼吸道，进行性出现三个渐进阶段（如图Phase1,2,3)，与此同时，临床观查到的症状、体征变化以及相应的可能有效治疗方法(左侧)。
目前比较明确的是临床辅助治疗需要避免进入细胞炎性风暴阶段：Phase1早期症状或轻微症状是积极治疗控制恶化的关键时期。
新冠病*感染过程及诱发"炎性风暴"
StageI(mild)–EarlyInfection:
Theinitialstageoccursatthetimeofinoculationandearlyestablishmentofdisease.Formostpeople,thisinvolvesanincubationperiodassociatedwithmildandoftennon-specificsymptomssuchasmalaise,feverandadrycough.Duringthisperiod,SARS-CoV-2multipliesandestablishesresidenceinthehost,primarilyfocusingontherespiratorysystem.Similartoitsolderrelative,SARS-CoV(responsibleforthe-SARSoutbreak),SARS-CoV-2bindstoitstargetusingtheangiotensin-convertingenzyme2(ACE2)receptoronhumancells.Thesereceptorsareabundantlypresentonhumanlungandsmallintestineepithelium,aswellasthevascularendothelium.AsaresultoftheairbornemethodoftransmissionaswellasaffinityforpulmonaryACE2receptors,theinfectionusuallypresentswithmildrespiratoryandsystemicsymptoms.DiagnosisatthisstageincludesrespiratorysamplePCR,serumtestingforSARS-CoV-2IgGandIgM,alongwithchestimaging,